Gypsum is a very common type of ore/stone that spawns in rock layers throughout the world. It can be mined with any tier of Pickaxe, and is affected by pickaxe-related enchantments (such as Fortune)

JC screenshot - Gypsum blocks

Naturally occurring Gypsum deposits

When mined, each Gypsum block will drop 4 – 9 Gypsum Powder. Gypsum Powder forms the basis for mining many different types of larger or more delicate fossils (such as dinosaur bones and fossilized nests), as part of Plaster and Bandage.

Gypsum Powder can also be reassembled back into Gypsum blocks.

JC screenshot - Gypsum block recipe

Gypsum powder can be turned back into a Gypsum block

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